以下为部分代表性应用文章:

1. Liang-Yi Zhu, MS, Xiao-Yu Wu, MS, Xiao-Dan Liu, PhD, Dan-Feng Zheng, MD, Hai-Shuang Li, MS, Bao Yang, MD, Jing Zhang, MD, PhD, Qing Chang, MD, PhD, Aggressive Medulloblastoma-Derived Exosomal miRNAs Promote In Vitro Invasion and Migration of Tumor Cells Via Ras/MAPK Pathway, Journal of Neuropathology & Experimental Neurology, Volume 79, Issue 7, July 2020, Pages 734-745, https://doi.org/10.1093/jnen/nlaa041.

2. Jiajia Gao, Lusong Tian, Yulin Sun, Wei Li, Lina Zhao, Yan Sun, Zongpan Jing, Lanping Zhou, Fang Liu, Xiaohang Zhao. PURα mediates epithelial-mesenchymal transition to promote esophageal squamous cell carcinoma progression by regulating Snail2. Cancer Letters, Volume 498,2021,Pages 98-110,ISSN 0304-3835, https://doi.org/10.1016/j.canlet.2020.10.030.

3. Shuxuan Li, Fenglin Liu, Ling Xu, Can Li, Xu Yang, Bao Guo, Jianxin Gu and Lan Wang. Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial–Mesenchymal Transition. Mol Cancer Res November 1 2020 (18) (11) 1650-1659; DOI: 10.1158/1541-7786.MCR-20-0180.

4. Shusen Zhang, Yuanyuan Lu, Lei Qi, Hongyan Wang, Zhihua Wang, Zhigang Cai, AHNAK2 Is Associated with Poor Prognosis and Cell Migration in Lung Adenocarcinoma, BioMed Research International, vol. 2020, Article ID 8571932, 14 pages, 2020. https://doi.org/10.1155/2020/8571932.

5. Yu Sun, Sheng-Hua Li, Ji-Wen Cheng, Gang Chen, Zhi-Guang Huang, Yong-Yao Gu, Hai-Biao Yan, Mao-Lin He, "Downregulation of miRNA-205 Expression and Biological Mechanism in Prostate Cancer Tumorigenesis and Bone Metastasis", BioMed Research International, vol. 2020, Article ID 6037434, 17 pages, 2020. https://doi.org/10.1155/2020/6037434.

6. Wu, W, Zhao, Y, Gao, E, et al. LncRNA DLEU2 accelerates the tumorigenesis and invasion of non–small cell lung cancer by sponging miR‐30a‐5p. J Cell Mol Med. 2020; 24: 441– 450. https://doi.org/10.1111/jcmm.14749.

7. Kong Jian, Yao Changyu, Ding Xuemei, Dong Shuying, Wu Shilun, Sun Wenbing, Zheng Lemin. ATPase Inhibitory Factor 1 Promotes Hepatocellular Carcinoma Progression After Insufficient Radiofrequency Ablation, and Attenuates Cell Sensitivity to Sorafenib Therapy. Frontiers in Oncology. 2020(10) 1080. https://www.frontiersin.org/article/10.3389/fonc.2020.01080.

8. Mengge Li, Min Du, Hui Cong, Yuanyuan Gu, Yuan Fang, Jin Li, Yu Gan, Hong Tu, Jinyang Gu, Qiang Xia, Characterization of hepatitis B virus DNA integration patterns in intrahepatic cholangiocarcinoma, Hepatology Research, 10.1111/hepr.13580, 0, 0, (2020).

9. Yang, Y., Lin, Z., Chen, J. et al. Autophagy in spinal ligament fibroblasts: evidence and possible implications for ossification of the posterior longitudinal ligament. J Orthop Surg Res 15, 490 (2020). https://doi.org/10.1186/s13018-020-02017-6.

10. Zhu T, Gao Z, Yuan K, Wang Y. High expression of RAD21 predicts poor survival in patients with operated non-small-cell lung cancer. Tumori Journal. 2020;106(3):223-228. doi:10.1177/0300891620910805.

11. Yang, Y, Lin, Z, Cheng, J, et al. The roles of autophagy in osteogenic differentiation in rat ligamentum fibroblasts: Evidence and possible implications. The FASEB Journal. 2020; 34: 8876– 8886. https://doi.org/10.1096/fj.201903216RR.

12. Junhui Xue, Zhengyi Cao, Yuning Cheng, Jiyin Wang, Yujuan Liu, Ruixiang Yang, Hui Li, Wei Jiang, Gang Li, Wenhui Zhao, Xiaowei Zhang, Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression, Cancer Letters,Volume 471,2020, Pages 12-26, https://doi.org/10.1016/j.canlet.2019.11.043.

13. Chen, T., Dai, X., Dai, J. et al. AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway. Cell Death Dis 11, 822 (2020). https://doi.org/10.1038/s41419-020-03030-7.

14. Zhang, J., Xiao, C., Feng, Z. et al. SOX4 promotes the growth and metastasis of breast cancer. Cancer Cell Int 20, 468 (2020). https://doi.org/10.1186/s12935-020-01568-2.

15. Song, Y., Wang, M., Tong, H. et al. Plasma exosomes from endometrial cancer patients contain LGALS3BP to promote endometrial cancer progression. Oncogene (2020). https://doi.org/10.1038/s41388-020-01555-x.

16. Hou Y, Wang W, Zeng Z, et al. High SEMA4C expression promotes the epithelial-mesenchymal transition and predicts poor prognosis in colorectal carcinoma. Aging (Albany NY). 2020;12(21):21992-22018. doi:10.18632/aging.104038.

17. Zhou, Y., Liu, F., Xu, Q. et al. Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer. Oncogene 39, 5633–5648 (2020). https://doi.org/10.1038/s41388-020-1384-3.

18. Zhou, Lijie & Zhengshuai, & Song, & Hu, Junyi & Liu, Lilong & Zhang, Xiaoping & Yang, Xiong & Chen, Ke. (2021). ACSS3 represses prostate cancer progression through downregulating lipid droplet-associated protein PLIN3. Theranostics. 11. 841-860. 10.7150/thno.49384.

19. Xie, P., Peng, Z., Chen, Y. et al. Neddylation of PTEN regulates its nuclear import and promotes tumor development. Cell Res (2020). https://doi.org/10.1038/s41422-020-00443-z.

2020年应用文献	组织芯片
PCR芯片	蛋白芯片	细胞
组织	血清血浆	RNA
高通量测序样品制备要求	石蜡标本